A Cysteine Protease Is Critical for Babesia spp. Transmission in Haemaphysalis Ticks

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A Cysteine Protease Is Critical for Babesia spp. Transmission in Haemaphysalis Ticks

Vector ticks possess a unique system that enables them to digest large amounts of host blood and to transmit various animal and human pathogens, suggesting the existence of evolutionally acquired proteolytic mechanisms. We report here the molecular and reverse genetic characterization of a multifunctional cysteine protease, longipain, from the babesial parasite vector tick Haemaphysalis longico...

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ژورنال

عنوان ژورنال: PLoS Pathogens

سال: 2008

ISSN: 1553-7374

DOI: 10.1371/journal.ppat.1000062